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Yu D, Xu F, Zeng J, Zhan J. Type III polyketide synthases in natural product biosynthesis. Wakimoto T, Mori T, Morita H, Abe I. Cytotoxic tetramic acid derivative produced by a plant type-III polyketide synthase. Wanibuchi K, Zhang P, Abe T, et al. Morita H, Yamashita M, Shi SP, et al. Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase. Condurso HL, Bruner SD. Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.
New pacidamycin antibiotics through precursor-directed biosynthesis. Xie Y, Cai Q, Ren H, et al. NRPS substrate promiscuity leads to more potent antitubercular sansanmycin analogues. Ragab AE, Gruschow S, Rackham EJ, Goss RJ.
New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity. Zhang W, Ntai I, Bolla ML, et al.
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. Kreutzer MF, Kage H, Herrmann J, et al. Precursor-directed biosynthesis of micacocidin derivatives with activity against Mycoplasma pneumoniae. Production of anticancer polyenes through precursor-directed biosynthesis. Ratnayake AS, Janso JE, Feng X, Schlingmann G, Goljer I, Carter GT. Evaluating indole-related derivatives as precursors in the directed biosynthesis of diazepinomicin analogues.
Dutta S, Whicher JR, Hansen DA, et al. Structure of a modular polyketide synthase. Whicher JR, Dutta S, Hansen DA, et al. Structural rearrangements of a polyketide synthase module during its catalytic cycle. McDaniel R, Thamchaipenet A, Gustafsson C, Fu H, Betlach M, Ashley G. Baltz RH, Miao V, Wrigley SK.
Natural products to drugs: daptomycin and related lipopeptide antibiotics. Doekel S, Coeffet-Le Gal MF, Gu JQ, Chu M, Baltz RH, Brian P. Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus.
Nguyen KT, He X, Alexander DC, et al. Genetically engineered lipopeptide antibiotics related to A54145 and daptomycin with improved properties. Baltz RH, Brian P, Miao V, Wrigley SK. Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporus. J Ind Microbiol Biotechnol. Staunton J, Weissman KJ. Polyketide biosynthesis: a millennium review. Crawford JM, Townsend CA. New insights into the formation of fungal aromatic polyketides.
Sun H, Ho CL, Ding F, Soehano I, Liu XW, Liang ZX. Synthesis of (R)-mellein by a partially reducing iterative polyketide synthase. Fisch KM, Bakeer W, Yakasai AA, et al. Rational domain swaps decipher programming in fungal highly reducing polyketide synthases and resurrect an extinct metabolite. Liu T, Chiang YM, Somoza AD, Oakley BR, Wang CC.
Liu T, Sanchez JF, Chiang YM, Oakley BR, Wang CC.