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Medicinal chemists are indispensable in the preclinical stages of drug development, and again as pharmaceutical chemists in drug quality control. Green chemistry is considered as frontiers of interdisciplinary science and is used to design chemical products roche labdoc procedures that reduce the generation of hazardous chemical substances.

Green chemistry has come a long way since its birth in 1991, growing from a small grassroot idea into a new approach to scientifically based environmental books about natural organic matters. It is also known as sustainable chemistry. Green chemistry applies the life cycle of a chemical product, including its manufacture, use, design, and ultimately disposal. Green chemistry is very helpful in the prevention of pollution at the molecular level and provides innovative scientific solutions.

It is able to reduce the negative impacts books about natural organic matters chemical products on human health. The main aspects of Green chemistry are; prevent waste, design less hazardous chemical synthesis, design safer chemicals and products.

Green chemistry also plays an important role in the agriculture sector and has a very wide application in pharmaceutical industry in developing innovatory drug delivery methods which are less toxic and books about natural organic matters effective with minimum side effects and could help millions of patients.

At the beginning of this special issue, we called to Medicinal and Green Chemistry researchers to contribute their review articles to shed light on the above topic by touching following two subtopics: 1. This number is projected to triple by 2050. There is no effective pharmacological treatment for combating the disease to date. The ineffectiveness of current pharmacological interventions in AD has led scientists to search for more safe and effective alternative therapeutic agents.

Thus, natural products have become an important avenue for drug discovery in AD research. In this connection, polyphenols are natural products that have been shown to books about natural organic matters effective in the modulation of the type of neurodegenerative changes seen in AD, suggesting a possible therapeutic role. Actually, glioblastoma is one of the most aggressive and devastating tumours of the central nervous system with short survival time.

Glioblastoma usually shows fast cell proliferation and invasion to normal brain tissue causing poor prognosis. The present standard of care in patients with glioblastoma books about natural organic matters surgery followed by radiotherapy and temozolomide based chemotherapy. Unfortunately, these approaches are not sufficient to lead a favourable prognosis and survival rates.

As the current approaches do not provide a long-term benefit in those patients, new alternative treatments, including natural compounds, have drawn attention. Due to their natural origin, they are associated with minimum cellular toxicity towards normal cells and it has become one of the most attractive approaches to treat tumours by natural compounds or phytochemicals.

In their review, the role of natural compounds or phytochemicals in the treatment of glioblastoma described in the light of efficacy on various aspects of glioblastoma pathophysiology such as cell proliferation, apoptosis, cell cycle regulation, cellular signaling pathways, chemo-resistance and their role in combinatorial therapeutic approaches. Preclinical data available in the literature suggest that phytochemicals hold books about natural organic matters potential to books about natural organic matters translated into treatment modalities.

Suaeda is a halophytic genus belonging to the Amaranthaceae family and is able to survive in the high salted marsh areas of the world. Suaeda plants have the ability to biosynthesize natural substances with powerful antioxidant activity and are considered as a renewable source of energy, food and edible oil for a larger number of populations living in the harsh environment with high salinity and low fodmap diet conditions.

These plants also meet folk and alternative medicine needs. Mohammed encompassed in his review books about natural organic matters scientific literature related to folk medicinal uses of Suaeda plants, their nutritional values and chemical constituents. In addition, the biological trials applied for the Suaeda plants are also incorporated books about natural organic matters this review.

Mathematics pure and applied mathematics and review covers research from major science literature search engines books about natural organic matters other sites representing scientific literature, i.

The searches were programmed on the advance options available in the search engines and are latest up to November 2019. The searches were exhaustive and rechecked for accuracy. The study summarizes the uses of Suaeda plants as a remedy for various ailments due to their contents from the polyphenols and flavonoids. Medicinal Chemistry has played a critical role in evolving new products, resources and processes which inexorably correspond to our high standards of living.

Unfortunately, this has also caused deterioration books about natural organic matters human health and threats to the global environment, even deaths when highly exposed to certain chemicals, whether due to improper use, mishandling or disposal.

There are chemicals, which apart from being carcinogens, endocrine disruptors or neurotoxins, are also responsible for climate change and ozone depletion.

Certain chemicals are known to cause neurotoxicity and are having tendencies to damage the central as well as peripheral nervous system or brain by damaging neurons or cells which are responsible for transmitting and processing of signals. This has raised serious concerns for the use and handling of such chemicals and books about natural organic matters given the growth in a relatively new emerging field known as Green Chemistry that strives to achieve sustainability at the molecular level and has an ability to harness chemicals to meet environmental and economic goals.

ALS a progressive neurodegenerative disease affects motor cortex, brain stem and spinal cord, causing muscular weakness, spasticity, and hyperreflexia. In this review, Fayaz et al.

Ziziphus jujuba Mill belonging to the Rhamnaceae family and it has been consumed since ancient times as a medicine books about natural organic matters food. In the different traditional medical schools, Z. From the perspective of Islamic traditional medicine, Z. It can purify the blood and improve blood circulation, relieve internal books about natural organic matters and reduce inflammation.

Some therapeutic uses of Z. This special issue was written to enable an in-depth understanding of the special issue topic. As a result, a new approach can be developed towards drug development and clinical aspects for enhanced progress in management strategies of different disorders.

We wish to end this editorial by thanking Prof. Dimitra Going, the Editor-in-Chief, books about natural organic matters well as Akhtar Waheed (Sr.

Manager) along with all the contributing authors who have enthusiastically responded to our request in books about natural organic matters in this special issue of Medicinal Chemistry. I additionally extend my thanks to all peer reviewers for their time and expertise in reviewing individual contribution. Due to team efforts of such a great books about natural organic matters team-gifted with extensive experience in the arena of Medicinal and Green Chemistry, this special issue provides a scholarly and important resource of reference for the benefit of medical-researchers and those suffering from various diseases.

These data require us developing various computational methods to understand them. The knowledge behind the data also provide us an opportunity for disease treatment. Thus, the applications of computational methods in pharmacogenomics and pharmacoproteomics have become a very hot topic in drug design, drug target discovery and disease treatment.



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