Triamterene and Hydrochlorothiazide Tablets (Maxide)- Multum

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Localized gray degradation products gradually accumulated on the sample surface until the entire surface became dark gray by the 3rd day. Most of the visible degradation of MgY occurred between 5 and 7 days, and MgY completely degraded after 9 days. MgY degraded much more rapidly than any other sample types in DI water.

Figure 3 shows the mass change of the samples in DI water. Figure 4 shows the pH Triamterene and Hydrochlorothiazide Tablets (Maxide)- Multum of DI water after sample immersion.

Between 9 and 29 days, the pH of Triamterene and Hydrochlorothiazide Tablets (Maxide)- Multum water stabilized in the range of 8.

After 13 days, the pH started to decrease and reached 7. The green star above the error bar of MgY mass change at 456 hr indicates that one of the triplicate samples completely degraded (i. Once the degradation products covered the entire surface after 3 days, accumulation of white degradation products appeared near the center of the sample.

In Figure 5B, similar degradation products accumulated on the surface of cpMg and spread at a similar rate. The cpMg samples fragmented near the center at day 5 and the remaining fragments continued to degrade until completely dissolved after 27 days. The degradation layer was rough, porous, and heterogeneous, and migrated inward from the edge until it covered the Clindamycin Phosphate, Tretinoin (Ziana Gel)- FDA surface.

As shown in Figure 5D, localized white degradation products appeared on the surface of MgY after 1 hour of incubation in PBS and spread over entire surface in 2 days. The MgY samples started to release fragments from its edges after day 5 and completely degraded after 29 days. Figure 6 shows the mass change of the samples in PBS. For example, cpMg reached its peak mass in off label use shorter time (i.

After reaching the peak mass, the sample mass started to decrease gradually. It is interesting to point out that the mass change of all samples had much greater deviation Triamterene and Hydrochlorothiazide Tablets (Maxide)- Multum their respective mass change in DI water, as indicated by bigger error bars.

Inhomogeneous sample degradation in PBS may have contributed to the Triamterene and Hydrochlorothiazide Tablets (Maxide)- Multum variances. Figure 7 shows the pH change of PBS after sample immersion. Ethiodol (Ethiodized Oil)- FDA pH of the PBS containing MgY rapidly increased to 8.

There were significant interactions among alloy composition, sample surface type, and immersion media, as demonstrated through three-way factorial ANOVA analysis.

The dependent variable should be a direct indicator of the sample degradation. The pH data did not have homogenous variance, and thus was not suitable as the dependent variable in the statistical analysis. The data on sample mass change did not meet the criteria of normal distribution, either. Therefore, the log (sample lifetime) was introduced as the dependent variable because it had normal distribution and homogenous variance, which met the criteria for three-way factorial ANOVA.

The Triamterene and Hydrochlorothiazide Tablets (Maxide)- Multum lifetime was defined as the time point when the sample was considered completely degraded or its residual mass was less than 3 mg. The lifetime of the samples that never fully degraded (i. The different values for one factor are presented along the X axis, while the Y axis represents the log (sample lifetime).

Two different lines in each plot present the different values for the second factor. The relationships between these two factors are further affected by the third factor and are thus plotted side by side for comparison.

Two separate interaction plots with different values of the third factor were placed side by side for comparison.

Further...

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